Time to onset of effect* | Time to maximal effect* | |
Symptomatic therapy | ||
Pyridostigmine | 10 to 15 minutes | 2 hours |
Chronic oral immunotherapies | ||
Prednisone | 2 to 3 weeks | 5 to 6 months |
Azathioprine | ~12 months | 1 to 2 years |
Mycophenolate mofetil | 6 to 12 months | 1 to 2 years |
Cyclosporine | ~6 months | ~7 months |
Tacrolimus | ~6 months | ~12 months |
Antibody-based biologic therapies | ||
Fc receptor inhibitors | ||
Efgartigimod alfa | 2 to 3 weeks | ~4 weeks |
Rozanolixizumab | 2 to 3 weeks | ~4 weeks |
Complement inhibitors | ||
Eculizumab | 2 to 3 weeks | ~4 weeks |
Ravulizumab | 2 to 3 weeks | ~4 to 10 weeks |
Zilucoplan | 2 to 3 weeks | ~4 weeks |
B-cell depletion therapy | ||
Rituximab | 4 weeks | ~8 weeks |
Rapid immunotherapies | ||
Plasmapheresis | 1 to 7 days | 1 to 3 weeks |
Intravenous immune globulin | 1 to 2 weeks | 1 to 3 weeks |
Surgery | ||
Thymectomy | 1 to 10 years | 1 to 10 years |
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