Drug/formulation | Dosing recommendations | |||
Oseltamivir (Tamiflu)* | ||||
| 1 through 12 years | |||
Children ≥12 months should receive approximately 4 mg/kg per day orally divided into 2 doses for a 5-day treatment course | ||||
≤15 kg | >15 to 23 kg | >23 to 40 kg | >40 kg | |
60 mg/day orally divided into 2 doses for 5 days | 90 mg/day orally divided into 2 doses for 5 days | 120 mg/day orally divided into 2 doses for 5 days | 150 mg/day orally divided into 2 doses for 5 days | |
≥13 years | ||||
150 mg/day orally divided into 2 doses for 5 days | ||||
Baloxavir (Xofluza)Δ | ||||
| ≥5 years | |||
| ||||
Peramivir (Rapivab)* | ||||
| 6 months through 12 years | |||
12 mg/kg per dose IV as a single dose (maximum dose 600 mg) | ||||
≥13 years | ||||
600 mg IV as a single dose | ||||
Zanamivir (Relenza)◊ | ||||
| ≥7 years | |||
2 inhalations (10 mg total per dose) twice daily for 5 days§ |
IV: intravenously.
* Dose adjustment is necessary for patients with renal insufficiency.
¶ When dispensing the oral suspension of oseltamivir, providers and pharmacists must take care to provide a dosing device that matches the units of measure on the prescription.
Δ Baloxavir is available in Japan for the treatment of influenza in children <12 years of age who weigh at least 10 kg. Refer to Japanese prescribing information for dosing information for children <12 years of age.
◊ Zanamivir is not recommended for the treatment of hospitalized patients, because of limited data in patients with severe influenza. Zanamivir inhalation powder should not be reconstituted in any liquid formulation and is not recommended for use in nebulizers or mechanical ventilators.
§ Two doses should be administered on day 1, provided that the doses can be spaced at least 2 hours apart.Do you want to add Medilib to your home screen?