ISHLT CAV0 (Not significant): No detectable angiographic lesion. |
ISHLT CAV1 (Mild): Angiographic LM <50 percent, primary vessel with maximum lesion of <70 percent, or any branch stenosis <70 percent (including diffuse narrowing) without allograft dysfunction. |
ISHLT CAV2 (Moderate): Angiographic LM ≥50 percent*, a single primary vessel ≥70 percent, or isolated branch stenosis ≥70 percent in branches of two systems, without allograft dysfunction. |
ISHLT CAV3 (Severe): Angiographic LM ≥50 percent, two or more primary vessels ≥70 percent stenosis, or isolated branch stenosis ≥70 percent in all three systems; or ISHLT CAV1 or CAV2 with allograft dysfunction (defined as LVEF ≤45 percent) or evidence of significant restrictive physiology. |
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