Pentavalent human-bovine reassortant vaccine (RV5, PRV)[2] | Attenuated human rotavirus vaccine (RV1, HRV)[3,4] | |
Trade name | RotaTeq | Rotarix |
Serotypes contained | G1, G2, G3, G4, P1[8] | G1P[8] |
Presentation and dose | Ready-to-use squeezable tube: 2 mL | Ready to use:
Requires reconstitution:
|
Number of doses | 3 | 2 |
Recommended schedule | 2, 4, 6 months | 2, 4 months |
Minimum age first dose | 6 weeks | 6 weeks |
Maximum age first dose | ||
United States | 14 weeks, 6 days | 14 weeks, 6 days |
Europe | 12 weeks | 12 weeks |
Minimal interval between doses | 4 weeks | 4 weeks |
Maximum age last dose | ||
United States | 8 months, 0 days | 8 months, 0 days* |
Europe | 24 weeks | 24 weeks |
Oral applicator | Latex-free |
|
Contains thimerosal | No | No |
* The Advisory Committee on Immunization Practices recommends 8 months, 0 days as the maximum age for the last dose for both RV1 and RV5; this varies from the prescribing information for RV1, which indicates that the second dose be administered up to 24 weeks of age.[1,3,4]
¶ Contraindicated in children with a severe (anaphylactic) allergy to latex.Do you want to add Medilib to your home screen?