Cardiac remodeling after anterior myocardial infarction

Late ventricular enlargement, or remodeling, resulting from increased circumference and sphericity, produces a marked increase in volume. The late change in circumference is due to lengthening of contractile tissue rather than further expansion of the infarcted, noncontractile segment. The increased sphericity results from a rounding out of the sharp abnormalities in contour at the margins of the infarct.