Adverse event | Annual rate per 1000 women | RR (95% CI) | ||||
Placebo | Tamoxifen | |||||
≤49 years | ≥50 years | ≤49 years | ≥50 years | ≤49 years | ≥50 years | |
Cerebrovascular accident | 0.5 | 1.7 | 0.57 | 2.5 | 1.13 (0.39-3.36) | 1.47 (0.97-2.22) |
Transient ischemic attack | 0.44 | 1.10 | 0.25 | 1.09 | 0.57 (0.12-2.25) | 0.99 (0.56-1.76) |
Pulmonary embolism | 0.13 | 0.44 | 0.25 | 0.96 | 2.01 (0.29-22.19) | 2.16 (1.02-4.89) |
Deep vein thrombosis | 0.76 | 0.89 | 1.01 | 1.33 | 1.34 (0.59-3.10) | 1.49 (0.84-2.68) |
Invasive endometrial cancer | 0.82 | 0.58 | 1.16 | 3.08 | 1.42 (0.55-3.81) | 5.33 (2.47-13.17) |
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