Complications of medical therapy for IBD

Medication	Perioperative complications
Prednisone	Addisonian crisis Depression Adrenal insufficiency
Sulfasalazine	Neutropenia Blood dyscrasias Hypersensitivity
Azathioprine and 6-mercaptopurine	Leukopenia Thrombocytopenia Macrocytic anemia Bone marrow suppression Hepatotoxicity
Mesalamine	Diarrhea Nausea/vomiting Headache
Metronidazole	Convulsive disorders Peripheral neuropathy
Cyclosporine	Nephrotoxicity Hepatotoxicity
Biologic agents	Injection site reactions Infusion reactions Infections Demyelinating disease Heart failure Malignancy Induction of autoimmunity
Small molecules	Wound infection Delayed wound healing Thromboembolic events

IBD: inflammatory bowel disease.

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