Clinical characteristics |
Unusual sites |
Associated with active disease and better when disease controlled |
Associated with use of steroids (possibly indicating active disease) |
Recurrent |
Serious |
Younger age |
Abnormalities described |
Abnormal fibrinolysis |
Abnormal platelet aggregation |
Activated protein C increased |
Circulating immune complexes |
Decreased antithrombin III |
Factor V Leiden mutation |
Increased cytokines (interleukin-6, thrombopoietin) |
Increased factors V and VIII |
Increased plasminogen activator inhibitor |
Increased sedimentation rate, fibrinogen |
Lupus anticoagulant |
Thrombocytosis and leukocytosis (uniformly present in most studies) |
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