Facial features of a patient with acromegaly

(A, B) Facial aspect of a patient with acromegaly. The nose is widened and thickened, the cheekbones are obvious, the forehead bulges, the lips are thick, and the facial lines are marked. The forehead and overlying skin is thickened, sometimes leading to frontal bossing.
(C, D) Mandibular overgrowth leads to prognathism, maxillary widening, teeth separation, and jaw malocclusion.