Recommended pre-exposure vaccination schedules for anthrax vaccine absorbed[1]
Recommended pre-exposure vaccination schedules for anthrax vaccine absorbed[1]
Timing
Route
Dose
Priming doses (3 doses):
0 months
1 month
6 months
Intramuscular
0.5 mL
Initial booster doses (2 doses):
12 months
18 months
Ongoing booster doses:
For individuals with ongoing risk: Every year
For individuals who are not at high risk but want to maintain immunity: Every three years
Individuals may work in high-risk areas of exposure once they have completed the priming series. If an individual has completed the priming and initial booster doses but has not received a booster dose in the past year, prior to entering a high-risk area of inhalation exposure, he or she should receive an additional booster dose and delay entry until two weeks later; if immediate entry is required, antimicrobials should be given for two weeks following vaccination. Refer to other UpToDate content on antimicrobial use for post-exposure prophylaxis.
Reference:
Bower WA, Schiffer J, Atmar RL, et al. Use of Anthrax Vaccine in the United States: Recommendations of the Advisory Committee on Immunization Practices, 2019. MMWR Recomm Rep 2019; 68:1.