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Version August 2025
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Proposed classification systems for ductal carcinoma in situ
Proposed classification systems for ductal carcinoma in situ
Lagios*
Van Nuys•
EuropeanΔ
Low grade
Non-high grade without necrosis
Well differentiated
Intermediate grade
Non-high grade with necrosis
Intermediately differentiated
High grade
High grade
Poorly differentiated
Classification_of_DCIS.htm
* Adapted from Lagios MD, Margolin FR, Westdahl PR, Rose MR. Cancer 1989; 63:618.
• Silverstein MJ, Poller DN, Waisman JR, et al. Lancet 1995; 345:1154.
Δ Holland R, Peterse JL, Millis RR, et al. Semin Diagn Pathol 1994; 11:167.
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