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Albuterol by MDI 4 to 8 puffs every 20 minutes up to 1 hour, then every 1 to 4 hours, as needed. |
Albuterol by nebulizer 0.083% (2.5 mg/3 mL), 2.5 to 5 mg every 20 minutes for 3 doses and then 2.5 to 5 mg every 1 to 4 hours, as needed. |
Albuterol by continuous nebulization, administering 10 to 15 mg per hour. |
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By nebulizer, 500 mcg every 20 minutes for 3 doses, then as needed. Can be given simultaneously with beta2-agonist. |
By MDI, 4 to 8 inhalations every 20 minutes for 3 doses, then as needed. |
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For patients who can be managed at home: prednisone 40 to 60 mg per day in a single or divided dose. |
For patients who require hospitalization: prednisone 40 to 80 mg daily in a single or divided dose (or the equivalent dose of methylprednisolone* intravenously) until peak flow reaches 70% of predicted or personal best, and then taper as patient improves. |
For patients who have a life-threatening exacerbation, a higher initial dose of methylprednisolone, 60 to 80 mg every 6 to 12 hours, may be given intravenously, and then tapered as the patient improves, as above. |
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Intravenous magnesium sulfate 2 g infused over 20 minutes, in absence of renal insufficiency.* |
Subcutaneous terbutaline 0.25 mg every 20 minutes for up to 3 doses. |
MDI: metered dose inhaler.
* For patients with renal insufficiency, a baseline serum magnesium level is assessed. The decision to use intravenous magnesium requires consideration of the potential benefit in terms of asthma and the anticipated risk of hypermagnesemia based on the degree of renal insufficiency and baseline serum magnesium level.Do you want to add Medilib to your home screen?