Drug | Side effects | Approximate percentage (range) of patients with adverse effect* |
Nifurtimox | Anorexia and weight loss | 50 (17 to 70) |
Polyneuropathy¶ | 25 (15 to 36) | |
Nausea/vomiting | 15 (5 to 33) | |
Abdominal discomfort | 15 (9 to 25) | |
Headache | 15 (13 to 19) | |
Dizziness/vertigo | 15 (9 to 25) | |
Insomnia | 12 (10 to 19) | |
Nervous excitation, mood changes | 15 (9 to 27) | |
Myalgia | 12 (11 to 14) | |
Disorientation | 7 (6 to 10) | |
Paresthesia | 3 (2 to 3) | |
Leukopenia | <3 | |
Benznidazole | Allergic dermatitisΔ | 30 (14 to 50) |
Peripheral neuropathy¶ | 30 (0 to 43) | |
Anorexia and weight loss | 15 (6 to 24) | |
Insomnia | 5 (0 to 6) | |
Nausea and/or vomiting | 4 (2 to 6) | |
Leukopenia◊ | Rare | |
Thrombocytopenia◊ | Rare | |
Dysgeusia§ | Rare |
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