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Frequency of decreased IgG subclass concentrations in different populations

Frequency of decreased IgG subclass concentrations in different populations
Sample population Number Percent
IgG1 IgG2 IgG3 IgG4
Healthy children 3854 4.9 19.4 6.3 0.8
Healthy adults 162 8 3 1 1
Adults with suspected antibody defects 1175 28 17 13 9
Data from different populations showing the percentage of individuals with low serum levels of specific IgG subclasses.
IgG: immunoglobulin G.
Reproduced with permission from: Meulenbroek AJ, Zeijlemaker WP. Human IgG subclasses: Useful diagnostic markers for immunocompetence, 2nd edition, CLB, Amsterdam, The Netherlands 2000. Copyright © 2000 Sanquin Blood Supply Foundation.
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