CHOP-21 chemotherapy consists of four agents: Cyclophosphamide (Cytoxan), Doxorubicin (Adriamycin, Hydroxydaunomycin), Vincristine (Oncovin), and Prednisone. One complete course is given every 21 days. Full treatment usually consists of six to eight such courses. | ||
Drug | Dose and route[1,2] | Given on day(s) |
Cyclophosphamide | 750 mg/m2 IV | Day 1 |
Doxorubicin | 50 mg/m2 IV | Day 1 |
Vincristine | 1.4 mg/m2 IV (maximum 2 mg) | Day 1 |
Prednisone | 100 mg per day orally | Days 1 through 5 |
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