Comorbidities |
Asthma |
Other pulmonary diseases (eg, COPD, interstitial lung disease) |
Cardiovascular diseases (eg, ischemic heart disease, hypertensive vascular disease, cardiomyopathy) |
Mast cell disorder (ie, systemic mastocytosis or mast cell activation syndrome) |
Concurrently administered medications |
Beta-adrenergic blockers* |
Alpha-adrenergic blockers¶ |
Angiotensin-converting enzyme (ACE) inhibitorsΔ |
Angiotensin II receptor blockersΔ |
Tricyclic antidepressants◊ |
Monoamine oxidase inhibitors§ |
ADHD medications¥ (eg, stimulants, such as methylphenidate and amphetamines) |
Recreational use of cocaine‡ |
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