Obstruction |
|
Infection¶ |
Viral
|
Bacterial
|
Protozoal
|
Genetic/metabolic disorders |
Inherited cholestatic disorders
|
Disorders of carbohydrate metabolism
|
Disorders of amino acid metabolism
|
Disorders of lipid metabolism
|
Disorders of bile acid synthesis
|
Mitochondrial disorders¥ |
Urea cycle defect
|
Congenital disorders of glycosylation
|
Alloimmune |
|
Toxic |
|
Miscellaneous |
|
HIV: human immunodeficiency virus.
¶ More common disorders causing neonatal cholestasis.
Δ Alagille syndrome is also known as syndromic paucity of the interlobular bile ducts or arteriohepatic dysplasia.
◊ These disorders are classified as secondary bile acid metabolic defects.
§ Presentation of Dubin-Johnson syndrome in neonates and young infants is rare but has been reported[3].
¥ For mitochondrial hepatopathies, refer to UpToDate table and content on acute liver failure in infants and children.Do you want to add Medilib to your home screen?