Blood smear from a patient with T cell prolymphocytic leukemia. The tumor cells are medium-sized lymphoid cells with moderately condensed chromatin and a prominent nucleolus. In T-PLL, the nucleus can be round or oval and the cytoplasm is slightly basophilic without granules. Cytoplasmic protrusions (blebs) are common.
Kindly provided by Sarayu Chandrashekhar, MD, Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA.
