Equivalent doses (mg) | Antiinflammatory activity relative to hydrocortisone* | Duration of action (hours) | |
Glucocorticoids | |||
Short acting | |||
Hydrocortisone (cortisol) | 20 | 1 | 8 to 12 |
Cortisone acetate | 25 | 0.8 | 8 to 12 |
Intermediate acting | |||
Prednisone | 5 | 4 | 12 to 36 |
Prednisolone | 5 | 4 | 12 to 36 |
Methylprednisolone | 4 | 5 | 12 to 36 |
Triamcinolone | 4 | 5 | 12 to 36 |
Long acting | |||
Dexamethasone | 0.75 | 30 | 36 to 72 |
Betamethasone | 0.6 | 30 | 36 to 72 |
Mineralocorticoids | |||
Fludrocortisone | Not used for an antiinflammatory effect¶. The typical dose of fludrocortisone for mineralocorticoid replacement is 0.1 to 0.2 mg. | 12 to 36 |
* Equivalent antiinflammatory dose shown is for oral or intravenous (IV) administration. Relative potency for intraarticular or intramuscular administration may vary considerably.
¶ The antiinflammatory potency is 10 to 15 times that of hydrocortisone; however, fludrocortisone is not used clinically as an antiinflammatory agent.Do you want to add Medilib to your home screen?