At least 20% improvement in: |
1. Swollen joint count |
2. Tender joint count |
and 3 of the following 5 variables: |
3. Patient-assessed global disease activity (eg, by VAS) |
4. Evaluator-assessed global disease activity (eg, by VAS) |
5. Patient pain assessment (eg, by VAS) |
6. Functional disability (eg, by HAQ) |
7. Acute phase response (ESR or CRP) |
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