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Suggestive and atypical features of relapsing-remitting multiple sclerosis

Suggestive and atypical features of relapsing-remitting multiple sclerosis
Suggestive features
  • Relapses and remissions
  • Onset between ages 15 and 50 years
  • Optic neuritis
  • Lhermitte sign
  • Internuclear ophthalmoplegia
  • Fatigue
  • Heat sensitivity (Uhthoff phenomenon)
Atypical features
  • Steady progression
  • Onset before age 10 or after age 50 years
  • Cortical deficits such as aphasia, apraxia, alexia, or neglect
  • Rigidity or sustained dystonia
  • Convulsions
  • Early dementia
  • Deficit developing within minutes
Graphic 63940 Version 7.0