Features suggestive of multiple sclerosis |
Relapses and remissions |
Onset between ages 15 and 50 years |
Optic neuritis |
Lhermitte sign |
Internuclear ophthalmoplegia |
Fatigue |
Heat sensitivity (Uhthoff phenomenon) |
Features atypical for multiple sclerosis |
Steady progression |
Onset before age 10 or after age 50 years |
Cortical deficits such as aphasia, apraxia, alexia, or neglect |
Rigidity or sustained dystonia |
Convulsions |
Early dementia |
Deficit developing within minutes |
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