Suppression of HBV replication |
Clearance of HBV DNA from serum |
Clearance of HBeAg with or without the development anti-HBe antibodies |
Improvement in liver disease |
Normalization in ALT level |
Decrease in necroinflammatory activity on liver biopsies |
Eradication of HBV (which is seldom achieved) |
Clearance of HBsAg with or without the development of anti-HBs antibodies |
Clearance of HBV DNA from serum (by PCR); rare in patients who remain HBsAg positive |
Disappearance of HBV DNA from liver |
Prevention of cirrhosis and hepatocellular carcinoma and improvement in survival |
Scanty data |
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