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Regulation of excitation-contraction coupling

Regulation of excitation-contraction coupling
Schematic representation of the factors responsible for regulation of the calcium transient at the sarcoplasmic reticulum (top) and of the regulation of excitation-contraction coupling by the binding of calcium to troponin C.
SERCA: sarco/endoplasmic reticulum calcium transporting ATPase; RyR2: Ryanodine receptor 2; DAG: diacylglycerol; IP3: inositol triphosphate.
Courtesy of Timothy W Smith, MD, PhD.
Graphic 62842 Version 3.0