Eruptive xanthoma

This 37-year-old female patient underwent in vitro fertilization and was treated with 800 mg of progesterone each day for 7 days. She developed cholestasis; jaundice; and small, pruritic papules on the elbows, hands, and knees. She had a family history of diabetes but was free of disease. Blood tests were characteristic of type IV hyperlipoproteinemia with hypertriglyceridemia, hypercholesterolemia, decreased low-density lipoproteins, decreased high-density lipoproteins, and elevated liver enzymes.