Agent | Number of patients studied | Dose | Response | Duration of response | Author; year |
Doxorubicin | 1 | 70 mg/m2 every three weeks Dose reduced after two cycles to 50 mg/m2 Cumulative dose of 450 mg/m2 | PR | >4 years after cessation of chemotherapy | Seiter K; 1993 |
Doxorubicin | 6 | NR | 3 PR | NR | de Camargo VP; 2010 |
Epirubicin | 1 | 30 mg/m2 every three weeks | PR | >1 year | Giaccone G; 1989 |
Pegylated liposomal doxorubicin | 1 adult 3 children | 20 to 50 mg/m2 Cumulative dose of 160 to 430 mg/m2 | 3 PR 1 SD | 9 to 40 months of follow-up, no progression seen | Wehl G; 2004 |
Pegylated liposomal doxorubicin | 22 | NR | 8 PR | NR | de Camargo VP; 2010 |
Pegylated liposomal doxorubicin | 14 | 40 to 50 mg/m2 every four weeks, up to six cycles | 4 PR 10 SD | 9 to 45 months | Constantinidou A; 2010 |
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