Drug | Dose | |
Adults | Children | |
Drugs of choice | ||
Tinidazole* | 2 g orally, single dose¶ | Age ≥3 years: 50 mg/kg orally, single dose (maximum dose 2 g) |
NitazoxanideΔ | 500 mg orally 2 times per day for 3 days | Age 1 to 3 years: 100 mg orally 2 times per day for 3 days Age 4 to 11 years: 200 mg orally 2 times per day for 3 days Age ≥12 years: Same as adult dose |
Alternative agents | ||
Metronidazole◊ | 500 mg orally twice daily OR 250 mg orally 3 times per day; duration 5 to 7 days¶ | 15 mg/kg orally divided 3 times per day for 5 to 7 days (maximum 250 mg per dose) |
Albendazole | 400 mg orally once daily for 5 days | 10 to 15 mg/kg orally once daily for 5 days (maximum 400 mg per dose) |
Mebendazole | 200 mg orally 3 times per day for 5 days | 200 mg orally 3 times per day for 5 days |
Paromomycin§ | 10 mg/kg orally 3 times per day for 5 to 10 days | 10 mg/kg orally 3 times per day for 5 to 10 days |
Furazolidone¥ | 100 mg orally 4 times per day for 7 to 10 days | 2 mg/kg orally 4 times per day for 7 to 10 days (maximum 100 mg per dose) |
Quinacrine | 100 mg orally 3 times per day for 5 days | 2 mg/kg orally 3 times per day for 5 days (maximum 100 mg per dose)‡ |
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