Antihypertensive dose response to thiazide therapy

Antihypertensive response to bendrofluazide in relation to daily dose (in mg; multiply by 10 to get approximate equivalent doses of hydrochlorothiazide). The initial dose of 1.25 mg/day lowers the blood pressure in comparison with placebo; however, higher doses produced little further antihypertensive response. Each treatment group contained approximately 52 patients.