Agents | Immunologic reactions | Nonimmunologic | |
IgE-mediated | Non-IgE-mediated | ||
Neuromuscular-blocking agents | + | – | + |
Antibiotics | + (eg, beta-lactams) | +/– | + (eg, vancomycin) |
Chlorhexidine | + | +/– | – |
Blue dyes (aka vital dyes) | + | – | +/– |
Hypnotic induction agents: | |||
Barbiturates | + | + | + |
Nonbarbiturates | +/– | + | + |
Opioids | +/– | – | + |
Colloids and plasma expanders | + | + | + |
Sugammadex | + | – | +/– |
Latex | + | – | – |
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