Overview of T cell activation and proliferation showing the site of action of available and experimental immunomodulatory agents

Reproduced with permission from: Vierling, JM. Clinical Use of Immunosuppressive Drugs to Control the Immune Response. In: Liver Immunology: Principles and Practice, Gershwin, ME, Vierling, JM, Manns, MP (Eds), Humana Press, Totowa 2007. Copyright ©2007 Springer-Verlag.