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Version August 2025
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Cytotoxic chemotherapy agents causing pigmentation changes
Cytotoxic chemotherapy agents causing pigmentation changes
Diffuse
Hair
Methotrexate
Busulfan
Liposomal doxorubicin
Hydroxyurea
Procarbazine
Fluorouracil
Cisplatin
Cyclophosphamide
Methotrexate
Combination regimens
Local
Special patterns*
Bleomycin
Cyclophosphamide
Busulfan
Doxorubicin (nonencapsulated)
Ifosfamide
Tegafur
Mitoxantrone
Daunorubicin
Capecitabine
Cisplatin
Carmustine
Mechlorethamine
Thiotepa
Docetaxel
Hydroxyurea
Fluorouracil
Vinorelbine
Fotemustine
Vincristine
Bromodeoxyuridine
Docetaxel
Bleomycin
Combination regimens
* Supravenous serpentine hyperpigmentation, flagellate hyperpigmentation, or hypopigmentation.
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