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Paraneoplastic cerebellar degeneration

Paraneoplastic cerebellar degeneration
Light micrograph shows paraneoplastic cerebellar degeneration in a patient with anti-Yo antibodies, which are directed against Purkinje cell antigens. There is total absence of Purkinje cells and Bergmann gliosis.
Courtesy of Josep Dalmau, MD, PhD.
Graphic 60259 Version 1.0