Sources of serum androgens in women with PCOS

Androgen	Ovary	Adrenal	Peripheral conversion
DHEAS	<5	>95	0
A	60	35	5 (from DHEAS)
T	60	5	35 (from A)
DHT	0	0	100 (from A and T)
3-androstanediol glucuronide	0	0	100 (from DHT)

Values are percent of total production at the different sites.

PCOS: polycystic ovarian syndrome; DHEAS: dehydroepiandrosterone sulfate; A: androstenedione; T: testosterone; DHT: dihydrotestosterone.

Graphic 60049 Version 4.0