Treatments with demonstrated efficacy |
Selective serotonin reuptake inhibitors |
Agents that suppress ovulation |
Combined estrogen-progestin oral contraceptives (COCs) |
COC containing 20 mcg EE/3 mg drospirenone |
Continuous administration COC containing 20 mcg EE/90 mcg levonorgestrel |
Gonadotropin-releasing hormone (GnRH) agonists |
Alprazolam (but not recommended) |
Treatments with possible efficacy |
Cyclic oral contraceptives (not containing drospirenone) |
Exercise |
Vitex agnus castus |
Ineffective treatments |
Progesterone |
Vitamin supplements |
Other herbal supplements |
Dietary restrictions |
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