Nonurgent oral premedication: |
Glucocorticoid-preferred regimen: |
Adult: Oral prednisone 50 mg at 13, 7, and 1 hour prior to contrast administration. |
Pediatric: Oral prednisone 0.5 to 0.7 mg/kg (maximum 50 mg per dose) at 13, 7, and 1 hour prior to contrast administration. |
Glucocorticoid-alternate: |
Adult: Oral methylprednisolone 32 mg at 12 and 2 hours prior to contrast administration. |
Pediatric: Oral methylprednisolone 1 mg/kg (maximum 32 mg per dose) at 12 and 2 hours prior to contrast administration. |
AND |
H1 antihistamine:* |
Adult: Diphenhydramine 50 mg oral, IM, or IV 1 hour prior to contrast administration. |
Pediatric: Diphenhydramine 1.25 mg/kg oral, IM, or IV (maximum 50 mg) 1 hour prior to contrast administration. |
Urgent intravenous premedication (eg, inpatients, emergency department):¶ |
Hydrocortisone 200 mg IV 5 hours and 1 hour prior to contrast administration and diphenhydramine 50 mg IV 1 hour prior to contrast administration.* |
Methylprednisolone 40 mg IV 5 hours and 1 hour prior to contrast medium administration and diphenhydramine 50 mg IV 1 hour prior to contrast administration.* |
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