(HBeAg-positive) | (HBeAg-negative) | |||
Entecavir 0.5 mg (n = 354) | Lamivudine 100 mg (n = 355) | Entecavir 0.5 mg (n = 325) | Lamivudine 100 mg (n = 313) | |
HBV DNA* | ||||
Proportion undetectable (<300 copies/mL) | 67 percent¶ | 36 percent | 90 percent¶ | 72 percent |
Mean changes from baseline (log10 copies/mL) | -6.86¶ | -5.39 | -5.04¶ | -4.53 |
ALT normalization (≤1 X ULN) | 68 percent¶ | 60 percent | 78 percent¶ | 71 percent |
HBeAg seroconversion | 21 percent | 18 percent | NA | NA |
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