Return To The Previous Page
Buy a Package
Number Of Visible Items Remaining : 3 Item

Cystic fibrosis incidence and carrier frequency by ancestry

Cystic fibrosis incidence and carrier frequency by ancestry
Group Incidence of cystic fibrosis Carrier frequency of a CFTR pathogenic variant F508del-CFTR (%)
Non-Hispanic White 1/3300 1/29 70
Hispanic 1/8000 to 9500 1/46 46
Ashkenazi Jewish 1/3300 1/29 30
Native American 1/3970 Pueblo 1/31 Pueblo 0
1/1580 Zuni 1/20 Zuni 0
African American 1/15,300 1/60 to 1/65 48
Asian 1/32,100 1/90 30
These carrier frequencies are based on a 23-variant panel, not the 100-variant panel proposed in 2023 and available here.
CFTR: cystic fibrosis conductance transmembrane regulator.
Data from:
  1. Genetic Testing for Cystic Fibrosis. National Institutes of Health Consensus Development Conference Statement on Genetic Testing for Cystic Fibrosis. Arch Intern Med 1999; 159:1529.
  2. American College of Obstetricians and Gynecologists. Committee Opinion No. 691: Carrier Screening for Genetic Conditions. Committee on Genetics. Obstet Gynecol 2017; 129:e41.
Graphic 58715 Version 8.0

Do you want to add Medilib to your home screen?