Schematic representation of the proposed structure of the calcium receptor cloned from bovine parathyroid tissue
Schematic representation of the proposed structure of the calcium receptor cloned from bovine parathyroid tissue
The structure of the human receptor is very similar.
SP: signal peptide; HS: hydrophobic substance; PKC: protein kinase C.
Adapted with permission from: Brown EM, Gamba G, Riccardi D, et al. Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid. Nature 1993; 366:575.