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Nonsteroidal antiinflammatory drugs (NSAIDs) in the treatment of desmoid tumors

Nonsteroidal antiinflammatory drugs (NSAIDs) in the treatment of desmoid tumors
Agents used Dose Number of patients Duration of therapy
(in months)
Response Duration of response Author; year
Meloxicam 10 mg/day 20 NR

1 CR

7 PR

11 SD

1 PD
NR Nishida Y; 2012
Sulindac 300 mg/day (median) 14 NR

1 CR

7 PR

4 SD

2 PD
NR Tsukada K; 1992
Indomethacin or sulindac or sulindac with warfarin   8 2 to 91 (median 20.5)

3 PR

3 SD

2 PD
NR Waddell W; 1991
Indomethacin 100 mg/day 3 4 to 10 (median 8)

1 CR

2 PD
NR Klein W; 1987
NR: not reported; CR: complete response; PR: partial response; SD: stable disease; PD: progressive disease.
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