Manifestation | Treatment |
Progressive disseminated histoplasmosis | |
Moderately severe to severe | Liposomal AmB* (3 mg/kg daily), AmB lipid complex* (5 mg/kg daily), or AmB deoxycholate* (0.7 to 1 mg/kg daily) for one to two weeks followed by itraconazole¶ (200 mg twice daily for at least 12 months) |
Mild to moderate | Itraconazole¶ (200 mg twice daily for at least 12 months) |
CNS histoplasmosis | Liposomal AmB* (5 mg/kg daily for four to six weeks) followed by itraconazole¶ (200 mg two to three times daily for at least 12 months) |
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