Situation | Agent | Adults | Children |
Oral | Amoxicillin | 2 g | 50 mg/kg |
Unable to take oral medication | Ampicillin | 2 g IM or IV | 50 mg/kg IM or IV |
or | |||
Cefazolin or ceftriaxone | 1 g IM or IV | 50 mg/kg IM or IV | |
Allergic to penicillin or ampicillin—oral | Cephalexin¶Δ | 2 g | 50 mg/kg |
or | |||
Azithromycin or clarithromycin | 500 mg | 15 mg/kg | |
or | |||
Doxycycline | 100 mg | <45 kg, 2.2 mg/kg >45 kg, 100 mg | |
Allergic to penicillin or ampicillin and unable to take oral medication | Cefazolin or ceftriaxoneΔ | 1 g IM or IV | 50 mg/kg IM or IV |
IM: intramuscular; IV: intravenous.
* Antibiotics should be administered 30 to 60 minutes prior to the procedure.
¶ Or other first- or second-generation oral cephalosporin in equivalent adult or pediatric dosing.
Δ Cephalosporins should not be used for patients with history of anaphylaxis, angioedema, or urticaria with penicillin or ampicillin. In such cases, vancomycin may be used (adults: 15 to 20 mg/kg IV, not to exceed 2 g per dose; children: 15 mg/kg IV to a maximum dose of 1 g).Do you want to add Medilib to your home screen?