Treatment | Cost | Multiple pregnancy risk | |
First line | Weight loss for high body mass index | Low | Not increased |
First line | Letrozole (alternative: clomiphene citrate) | Low | Low |
Second line | Follicle-stimulating hormone injections | High | High, includes high-order multiples |
Second line | Ovarian drilling | High | Not increased |
Third line | In vitro fertilization | Very high | High but reducible with single embryo transfer |
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