Circadian pattern of nonfatal myocardial infarction and sudden death

A meta-analysis was performed using trials that reported the timing for an acute myocardial infarction (n = 66,635 patients) and sudden death (n = 19,390 patients). An excess number of infarctions and sudden deaths occurred in the morning between the hours of 6 AM and 12 PM, indicating a circadian pattern to their occurrence.