Serum free light chains

This figure shows simultaneous measurements of free serum kappa (horizontal axis) and lambda (vertical axis) light chains. The dashed line indicates a 1:1 kappa/lambda ratio (weight basis). Results are shown for 282 normal subjects (+), 120 patients with kappa light chain myeloma (closed circles), 140 patients with lambda light chain myeloma (closed triangles), 31 patients with renal impairment from non light chain disorders (open squares), and 28 subjects with non-secretory myeloma (open circles). Note that monoclonality could be detected in many of the latter group using this technique.