Down syndrome screening test | Term risk cut-off* | Detection rate (%) | False-positive rate (%) | Positive predictive value (%)¶ |
Quadruple | 1:350 | 88 | 7.7 | 2.5 (1:39) |
CombinedΔ | 86 | 6.4 | 3 (1:33) | |
IntegratedΔ | 92 | 3.9 | 5 (1:19) | |
Quadruple | 1:300 | 86 | 6.6 | 3 (1:34) |
CombinedΔ | 84 | 5.5 | 3 (1:29) | |
IntegratedΔ | 91 | 3.4 | 6 (1:17) | |
Quadruple | 1:250 | 84 | 5.7 | 3 (1:30) |
CombinedΔ | 83 | 4.7 | 4 (1:25) | |
IntegratedΔ | 90 | 3.0 | 7 (1:14) | |
Quadruple | 1:200 | 82 | 4.7 | 4 (1:25) |
CombinedΔ | 81 | 3.8 | 5 (1:21) | |
IntegratedΔ | 89 | 2.4 | 8 (1:12) | |
Quadruple | 1:150 | 79 | 3.6 | 5 (1:20) |
CombinedΔ | 78 | 2.8 | 6 (1:16) | |
IntegratedΔ | 87 | 1.9 | 9 (1:10) | |
Quadruple | 1:100 | 74 | 2.5 | 7 (1:15) |
CombinedΔ | 75 | 1.9 | 8 (1:11) | |
IntegratedΔ | 85 | 1.3 | 12 (1:7) |
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