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Clinical features of obstructive sleep apnea

Clinical features of obstructive sleep apnea
Examination findings
  • Narrow or "crowded" oropharynx (eg, Mallampati 3 or 4; macroglossia, tonsillar enlargement, narrow palate)
  • Obesity
  • Large neck circumference (eg, >17 inches [males]; >16 inches [females])
  • Craniofacial abnormalities (eg, retrognathia)
Symptoms
  • Daytime sleepiness
  • Nonrestorative sleep or fatigue
  • Loud snoring
  • Witnessed apneas by bed partner
  • Awakening with choking or gasping
  • Nocturnal restlessness
  • Insomnia (initiation, maintenance, frequent awakenings)
  • Lack of concentration
  • Cognitive deficits (eg, short-term memory loss)
  • Changes in mood
  • Morning headaches
  • Vivid, strange, or threatening dreams
  • Nocturia
Associated conditions
  • Obesity hypoventilation syndrome
  • Systemic hypertension
  • Cardiovascular disease (eg, heart failure)
  • Cerebrovascular disease (eg, stroke, transient ischemic attacks)
  • Cardiac dysrhythmias (eg, atrial fibrillation)
  • Pulmonary hypertension
  • Cor pulmonale
  • End-stage kidney disease
  • Type 2 diabetes mellitus
  • Chronic lung disease
  • Pregnancy
  • Acromegaly
  • Hypothyroidism
  • Gastroesophageal reflux
  • Secondary polycythemia
  • Floppy eyelid syndrome
  • Polycystic ovary syndrome
  • Parkinson disease
  • Marfan or Ehlers-Danlos syndrome
  • Sleep-related bruxism
  • Fibromyalgia
For further information, refer to UpToDate content on clinical evaluation of OSA.
OSA: obstructive sleep apnea.
Graphic 55633 Version 19.0

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