Among 1252 subjects from the general population, median serum concentrations of N-terminal atrial natriuretic peptide (NT-ANP) and brain natriuretic peptide (BNP) were significantly higher in those with left ventricular systolic dysfunction (LVD) as assessed with echocardiography. Among the patients with LVD, 77% were asymptomatic. Boxes are median concentrations and vertical lines are the ranges.
Data from McDonagh TA, Robb SD, Murdoch DR, et al. Lancet 1998; 351:9.