(A) The lesion fills and expands lymph node sinuses, and the Langerhans cells are associated with eosinophils and giant cells. Hematoxylin-eosin stain.
(B) Immunostain for CD1a highlights numerous Langerhans cells. Immunochemistry with hematoxylin counterstain.
Reproduced with permission from: Ioachim HL, Medeiros LJ. Dendritic cell neoplasms. In: Ioachim's Lymph Node Pathology, 4th ed, Lippincott Williams & Wilkins, Philadelphia 2009. Copyright © 2009 Lippincott Williams & Wilkins.
www.lww.com.