Premenopausal women (refer if any are present) |
Very elevated CA 125 level* |
Ascites |
Evidence of abdominal or distant metastases |
Postmenopausal women (refer if any are present) |
Elevated CA 125 level* |
Ascites |
Nodular or fixed pelvic mass |
Evidence of abdominal or distant metastases |
ACOG: American College of Obstetricians and Gynecologists; CA 125: cancer antigen 125.
* These guidelines do not provide a specific value for an elevated (or very elevated) CA 125 level. While the 2002 version used a value of >200 units/mL, this was removed in 2011. Studies evaluating the performance of the 2002 guidelines showed that 70 to 79% of premenopausal and 93 to 94% of postmenopausal patients with ovarian cancer will be captured by this threshold (specificity 70 and 60%, respectively).Do you want to add Medilib to your home screen?