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Odds of Down syndrome after a positive test result based on data from the SURUSS trial

Odds of Down syndrome after a positive test result based on data from the SURUSS trial
Test Odds
First plus second trimester
Integrated 1 in 5
Serum integrated 1 in 20
Second trimester
Quadruple 1 in 32
First trimester
Combined 1 in 22
NT 1 in 94
These odds are obtained when each test is used to achieve an 85 percent detection rate.
SURUSS: Serum, Urine, and Ultrasound Screening Study; NT: nuchal translucency.
Adapted from: Wald NJ, Rodeck C, Hackshaw AK, Rudnicka A. BJOG 2004; 111:521.
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