Antigen-independent phase | Antigen-dependent phase | ||||||||
Pre-pro B cell | Pro-B cell | Pre B cell | Immature B cell | Mature B cell | Activated B cell | Blast B cell | Memory B cell | Plasma B cell | |
Surrogate light chain | S | S + IgM H chain | |||||||
Ig genes | GL | DJH | VDJH | VJL RE | CS SM RE | CS SM RE | |||
IgM | C, H chain only | S | S | S if no CS | S if no CS | S if no CS | S if no CS | ||
IgD | S |
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